Generic Methotrexate is an antimetabolite type of medicine. The action by which Methotrexate works is different in specific ailments for which it is taken. When treating cancerous ailments, Methotrexate action takes part in the cellular activity such as synthesizing DNA, correcting and replicating activity of the cells. Generic Methotrexate action is most effective against internal tissues that seem to multiplying at very high rate. This includes cancerous cells, urinary bladder cells, fetal cells, bone marrow etc. Whenever any abnormal growth rate of cells is observed, Methotrexate acts upon it and stops the abnormality from multiplying without making any permanent injury to the normal tissues. Similarly in case of psoriasis, the patients skin epithelial cell production is much higher than normal skin. Methotrexate stops this increased rate.
Yet, Methotrexate use should be monitored and carried out under proper physician supervision. There are quite a few side effects that can result from Methotrexate use. It may affect that patient’s hair; skin blistering or pimples may occur and the patient’s dietary capacity may reduce along with the weight. The patients may also suffer exhaustion or blisters in the mouth. Apart from this certain severe side effects include loose motions, flu like symptoms; skin irritation; bloating of joints in the lower body etc. When consulting with their physician, patients should reveal allergic substances especially if their allergies are related to Methotrexate or its other components.
Patients should disclose their medical history to their physician and should definitely reveal if they have had any intestinal problems; immune system troubles; ulcers; renal / hepatic problems etc. Users should also avoid vaccinations while undergoing Methotrexate medication. Patients should remember that Methotrexate might stop patients from conception (yet it is not a contraceptive product and necessary protection should be taken.) Irregular menstruation may occur while taking Methotrexate.
